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Télécharger la publication scientifique présentant les 1ers résultats de la cohorte (article en anglais)
2025
Aghetti A, Bouteloup V, Lebenberg J, Chupin M, Gourieux E, Mangin JF, Chêne G, Dufouil C, Jouvent E; behalf of the Memento Study Group. Superficial white matter hyperintensities are associated with mild tissue alterations in vascular aging. Rev Neurol (Paris). 2025 Apr 25:S0035-3787(25)00501-6. doi: 10.1016/j.neurol.2025.03.014. Epub ahead of print. PMID: 40287332.
Blanc F, Bouteloup V, Paquet C, Chupin M, Pasquier F, Gabelle A, Ceccaldi M, de Sousa PL, Krolak-Salmon P, David R, Fischer C, Dartigues JF, Wallon D, Moreaud O, Sauvée M, Belin C, Roubaud C, Botzung A, Ravier A, Demuynck C, Namer I, Habert MO, Bousiges O, Schorr B, Muller C, Philippi N, Chêne G, Cretin B, Mangin JF, Dufouil C. Cognitive and neuroimaging outcome of very prodromal dementia with Lewy bodies. Geroscience. 2025 May 25. doi: 10.1007/s11357-025-01701-x. Epub ahead of print. PMID: 40415136.
Bouteloup V, Villain N, Vidal JS, Gonzalez-Ortiz F, Yuksekel I, Santos C, Schraen-Maschken S, Pellegrin I, Lehmann S, Blennow K, Chêne G, Hanon O, Dufouil C, Planche V; MEMENTO and the BALTAZAR Study Groups. Cognitive Phenotyping and Interpretation of Alzheimer Blood Biomarkers. JAMA Neurol. 2025 May 1;82(5):506-515. doi: 10.1001/jamaneurol.2025.0142. PMID: 40181683; PMCID: PMC11971688.
Couvy-Duchesne B, Frouin V, Bouteloup V, Koussis N, Sidorenko J, Jiang J, Wink AM, Lorenzini L, Barkhof F, Trollor JN, Mangin JF, Sachdev PS, Brodaty H, Lupton MK, Breakspear M, Colliot O, Visscher PM, Wray NR; Alzheimer's Disease Neuroimaging Initiative; Australian Imaging Biomarkers and Lifestyle flagship study of ageing; Alzheimer's Disease Repository Without Borders Investigators; MEMENTO cohort Study Group. Grey-Matter Structure Markers of Alzheimer's Disease, Alzheimer's Conversion, Functioning and Cognition: A Meta-Analysis Across 11 Cohorts. Hum Brain Mapp. 2025 Feb 1;46(2):e70089. doi: 10.1002/hbm.70089. PMID: 39907291; PMCID: PMC11795582.
2024
Ackley S, Calmasini C, Bouteloup V, Hill-Jarrett TG, Swinnerton KN, Chêne G, Dufouil C, Glymour MM; Memento Cohort study group and DPUK. Contribution of Global Amyloid-PET Imaging for predicting Future Cognition in the MEMENTO Cohort. Neurology. 2024 Mar 26;102(6):e208054. doi:10.1212/WNL.0000000000208054. Epub 2024 Fev 27. PMID: 38412412.
Ahmad S, Imtiaz MA, Mishra A, Wang R, Herrera-Rivero M, Bis JC, Fornage M, Roshchupkin G, Hofer E, Logue M, Longstreth WT Jr, Xia R, Bouteloup V, Mosley T, Launer LJ, Khalil M, Kuhle J, Rissman RA, Chene G, Dufouil C, Djoussé L, Lyons MJ, Mukamal KJ, Kremen WS, Franz CE, Schmidt R, Debette S, Breteler MMB, Berger K, Yang Q, Seshadri S, Aziz NA, Ghanbari M, Ikram MA. Genome-wide association study meta-analysis of neurofilament light (NfL) levels in blood reveals novel loci related to neurodegeneration. Commun Biol. 2024 Sep 9;7(1):1103. doi: 10.1038/s42003-024-06804-3. PMID: 39251807
Andriuta D, Roussel M, Chene G, Fischer C, Mangin JF, Dubois B, Vellas B, Pasquier F, Tison F, Blanc F, Hanon O, Paquet C, Gabelle A, Ceccaldi M, Annweiler C, Krolak-Salmon P, David R, Rouch-Leroyer I, Benetos A, Moreaud O, Sellal F, Jalenques I, Vandel P, Bouteloup V, Godefroy O; MEMENTO Study Group. The pattern of cortical thickness associated with executive dysfunction in MCI and SCC: The MEMENTO cohort. Rev Neurol (Paris). 2024 Jun 11:S0035-3787(24)00534-4. doi: 10.1016/j.neurol.2024.02.394. PMID: 38866655
Bouteloup V, Pellegrin I, Dubois B, Chene G, Planche V, Dufouil C; MEMENTO Study Group. Explaining the Variability of Alzheimer Disease Fluid Biomarker Concentrations in Memory Clinic Patients Without Dementia. Neurology. 2024 Apr 23;102(8):e209219. doi: 10.1212/WNL.0000000000209219. Epub 2024 Mar 25. PMID: 38527237.
Grasset L, Bouteloup V, Cacciamani F, Pellegrin I, Planche V, Chêne G, Dufouil C; MEMENTO study group. Associations Between Blood-Based Biomarkers and Cognitive and Functional Trajectories Among Participants of the MEMENTO Cohort. Neurology. 2024 May;102(9):e209307. doi: 10.1212/WNL.0000000000209307. Epub 2024 Apr 16. PMID: 38626384; PMCID: PMC11175638.
Le Scouarnec L, Bouteloup V, van der Veere PJ, van der Flier WM, Teunissen CE, Verberk IMW, Planche V, Chêne G, Dufouil C. Development and assessment of algorithms for predicting brain amyloid positivity in a population without dementia. Alzheimers Res Ther. 2024 Oct 11;16(1):219. doi: 10.1186/s13195-024-01595-5. PMID: 39394180; PMCID: PMC11468062.
Lopez S, Hampel H, Chiesa PA, Del Percio C, Noce G, Lizio R, Teipel SJ, Dyrba M, González-Escamilla G, Bakardjian H, Cavedo E, Lista S, Vergallo A, Lemercier P, Spinelli G, Grothe MJ, Potier MC, Stocchi F, Ferri R, Habert MO, Dubois B, Babiloni C; INSIGHT-preAD study group. The association between posterior resting-state EEG alpha rhythms and functional MRI connectivity in older adults with subjective memory complaint. Neurobiol Aging. 2024 May;137:62-77. doi: 10.1016/j.neurobiolaging.2024.02.008. Epub 2024 Feb 28. PMID: 38431999.
Patel Y, Shin J, Sliz E, Tang A, Mishra A, Xia R, Hofer E, Rajula HSR, Wang R, Beyer F, Horn K, Riedl M, Yu J, Völzke H, Bülow R, Völker U, Frenzel S, Wittfeld K, Van der Auwera S, Mosley TH, Bouteloup V, Lambert JC, Chêne G, Dufouil C, Tzourio C, Mangin JF, Gottesman RF, Fornage M, Schmidt R, Yang Q, Witte V, Scholz M, Loeffler M, Roshchupkin GV, Ikram MA, Grabe HJ, Seshadri S, Debette S, Paus T, Pausova Z. Genetic risk factors underlying white matter hyperintensities and cortical atrophy. Nat Commun. 2024 Nov 4;15(1):9517. doi: 10.1038/s41467-024-53689-1. PMID: 39496600
Raposo Pereira F, Chaumon M, Dubois B, Bakardjian H, Bahrami M, Habert MO, Andrade K, Younsi N, La Corte V, George N; INSIGHT-preAD study group. Recognition memory decline is associated with the progression to prodromal Alzheimer's disease in asymptomatic at-risk individuals. J Neurol. 2024 Dec 16;272(1):70. doi: 10.1007/s00415-024-12834-y. PMID: 39680203.
Sargurupremraj M, Soumaré A, Bis JC, Surakka I, Jürgenson T, Joly P, Knol MJ, Wang R, Yang Q, Satizabal CL, Gudjonsson A, Mishra A, Bouteloup V, Phuah CL, van Duijn CM, Cruchaga C, Dufouil C, Chêne G, Lopez OL, Psaty BM, Tzourio C, Amouyel P, Adams HH, Jacqmin-Gadda H, Ikram MA, Gudnason V, Milani L, Winsvold BS, Hveem K, Matthews PM, Longstreth WT, Seshadri S, Launer LJ, Debette S. Genetic Complexities of Cerebral Small Vessel Disease, Blood Pressure, and Dementia. JAMA Netw Open. 2024 May 1;7(5):e2412824. doi: 10.1001/jamanetworkopen.2024.12824. PMID: 38776079
Tate AE, Bouteloup V, van Maurik IS, Jean D, Mank A, Speh A, Boilet V, van Harten A, Eriksdotter M, Wimo A, Dufouil C, van der Flier WM, Jönsson L. Predicting sojourn times across dementia disease stages, institutionalization, and mortality. Alzheimers Dement. 2024 Feb;20(2):809-818. doi: 10.1002/alz.13488. Epub 2023 Oct 1. PMID: 37779086
Rapos Pereira F, George N, Dalla Barba G, Dubois B, La Corte V; INSIGHT-preAD study group. The Memory Binding Test Detects Early Subtle Episodic Memory Decline in Preclinical Alzheimer's Disease: A Longitudinal Study. J Alzheimers Dis. 2024;98(2):465-479. doi: 10.3233/JAD-230921. PMID: 38393903.
2023
Aye S, Bouteloup V, Tate A, Wimo A, Handels R, Jean D, Winblad B, Jönsson L. Health-related quality of life in subjective cognitive decline and mild cognitive impairment: a longitudinal cohort analysis. Alzheimers Res Ther. 2023 Nov 15;15(1):200. doi: 10.1186/s13195-023-01344-0. PMID: 37968734; PMCID: PMC10648708.
Bogdan A, Fabre R, Desmidt T, Golebiowski J, Topin J, Bethus I, Hanon O, Boutoleau-Bretonniere C, Wagemann N, Annweiler C, Ousset PJ, Godefroy O, Rouch I, Paccalin M, Sukhorukova M, Gabelle A, Robert G, David R; Memento Group. Different Trajectories of Apathy and Depression Among Subjective Cognitive Impairment Individuals with or without Conversion to Dementia: Results from the Memento Cohort in France. J Alzheimers Dis. 2023 Aug 1. doi: 10.3233/JAD-230162. Epub ahead of print. PMID: 37545236.
Cacciamani F, Bercu A, Bouteloup V, Grasset L, Planche V, Chêne G, Dufouil C; MEMENTO Cohort Study Group. Understanding factors associated with the trajectory of subjective cognitive complaints in groups with similar objective cognitive trajectories. Alzheimers Res Ther. 2023 Nov 22;15(1):205. doi: 10.1186/s13195-023-01348-w. PMID: 37993894; PMCID: PMC10666380
Gallet Q, Bouteloup V, Locatelli M, Habert MO, Chupin M, Campion JY, Michels PE, Delrieu J, Lebouvier T, Balageas AC, Surget A, Belzung C, Arlicot N, Ribeiro MS, Gissot V, El-Hage W, Camus V, Gohier B, Desmidt T; MEMENTO study group. Cerebral Metabolic Signature of Chronic Benzodiazepine Use in Nondemented Older Adults: An FDG-PET Study in the MEMENTO Cohort. Am J Geriatr Psychiatry. 2023 Oct 19:S1064-7481(23)00445-1. doi: 10.1016/j.jagp.2023.10.002. Epub ahead of print. PMID: 37973486
Grasset L, Planche V, Bouteloup V, Azouani C, Dubois B, Blanc F, Paquet C, David R, Belin C, Jonveaux T, Julian A, Pariente J, Mangin JF, Chêne G, Dufouil C; Memento Cohort Study Group. Physical activity, biomarkers of brain pathologies and dementia risk: Results from the Memento clinical cohort. Alzheimers Dement. 2023 Jul 8. doi: 10.1002/alz.13360. Epub ahead of print. PMID: 37422285.
Ismail Z, Leon R, Creese B, Ballard C, Robert P, Smith EE. Optimizing detection of Alzheimer's disease in mild cognitive impairment: a 4-year biomarker study of mild behavioral impairment in ADNI and MEMENTO. Mol Neurodegener. 2023 Jul 29;18(1):50. doi: 10.1186/s13024-023-00631-6. PMID: 37516848; PMCID: PMC10386685.
Lespinasse J, Dufouil C, Proust-Lima C. Disease progression model anchored around clinical diagnosis in longitudinal cohorts: example of Alzheimer's disease and related dementia. BMC Med Res Methodol. 2023 Sep 5;23(1):199. doi: 10.1186/s12874-023-02009-0. PMID: 37670234; PMCID: PMC10478286.
Lespinasse J, Chêne G, Mangin JF, Dubois B, Blanc F, Paquet C, Hanon O, Planche V, Gabelle A, Ceccaldi M, Annweiler C, Krolak-Salmon P, Godefroy O, Wallon D, Sauvée M, Bergeret S, Chupin M, Proust-Lima C, Dufouil C; MEMENTO study group. Associations among hypertension, dementia biomarkers, and cognition: The MEMENTO cohort. Alzheimers Dement. 2023 Jun;19(6):2332-2342. doi: 10.1002/alz.12866. Epub 2022 Dec 4. PMID: 36464896.
Leroy V, Chen Y, Bouteloup V, Skrobala E, Puisieux F, Fougère B. What Tools Can We Use to Screen for Fall Risk in Older Patients with Mild Cognitive Impairment? Findings from the MEMENTO Cohort. J Am Med Dir Assoc. 2023 Jul;24(7):1028-1034.e18. doi: 10.1016/j.jamda.2022.12.020. Epub 2023 Jan 19. PMID: 36682387.
Maheux E, Koval I, Ortholand J, Birkenbihl C, Archetti D, Bouteloup V, Epelbaum S, Dufouil C, Hofmann-Apitius M, Durrleman S. Forecasting individual progression trajectories in Alzheimer's disease. Nat Commun. 2023 Feb 10;14(1):761. doi: 10.1038/s41467-022-35712-5. PMID: 36765056; PMCID: PMC9918533.
Planche V, Bouteloup V, Pellegrin I, Mangin JF, Dubois B, Ousset PJ, Pasquier F, Blanc F, Paquet C, Hanon O, Bennys K, Ceccaldi M, Annweiler C, Krolak-Salmon P, Godefroy O, Wallon D, Sauvee M, Boutoleau-Bretonnière C, Bourdel-Marchasson I, Jalenques I, Chene G, Dufouil C; MEMENTO Study Group. Validity and Performance of Blood Biomarkers for Alzheimer Disease to Predict Dementia Risk in a Large Clinic-Based Cohort. Neurology. 2023 Jan 31;100(5):e473-e484. doi: 10.1212/WNL.0000000000201479. Epub 2022 Oct 19. PMID: 36261295; PMCID: PMC9931079.
Sagaspe P, Amieva H, Dartigues JF, Olive J, de la Rivière JB, Chartier C, Taillard J, Philip P. Validity and diagnostic performance of a virtual reality-based supermarket application "MEMOSHOP" for assessing episodic memory in normal and pathological aging. Digit Health. 2023 Dec 21;9:20552076231218808. doi: 10.1177/20552076231218808. PMID: 38144175; PMCID: PMC10748669.
Sargurupremraj M, Soumare A, Bis JC, Surakka I, Jurgenson T, Joly P, Knol MJ, Wang R, Yang Q, Satizabal CL, Gudjonsson A, Mishra A, Bouteloup V, Phuah CL, van Duijn CM, Cruchaga C, Dufouil C, Chêne G, Lopez O, Psaty BM, Tzourio C, Amouyel P, Adams HH, Jacqmin-Gadda H, Ikram MA, Gudnason V, Milani L, Winsvold BS, Hveem K, Matthews PM, Longstreth WT, Seshadri S, Launer LJ, Debette S. Complexities of cerebral small vessel disease, blood pressure, and dementia relationship: new insights from genetics. medRxiv [Preprint]. 2023 Aug 13:2023.08.08.23293761. doi: 10.1101/2023.08.08.23293761. PMID: 37790435; PMCID: PMC10543241.
2022
Blanc F, Bouteloup V, Paquet C, Chupin M, Pasquier F, Gabelle A, Ceccaldi M, de Sousa PL, Krolak-Salmon P, David R, Fischer C, Dartigues JF, Wallon D, Moreaud O, Sauvée M, Belin C, Harston S, Botzung A, Albasser T, Demuynck C, Namer I, Habert MO, Kremer S, Bousiges O, Verny M, Muller C, Philippi N, Chene G, Cretin B, Mangin JF, Dufouil C. Prodromal characteristics of dementia with Lewy bodies: baseline results of the MEMENTO memory clinics nationwide cohort. Alzheimers Res Ther. 2022 Jul 19;14(1):96. doi: 10.1186/s13195-022-01037-0. PMID: 35854388; PMCID: PMC9295361.
Gallet Q, Bouteloup V, Locatelli M, Habert MO, Chupin M, Delrieu J, Lebouvier T, Robert G, David R, Bulteau S, Balageas AC, Surget A, Belzung C, Arlicot N, Ribeiro MJ, Barantin L, Andersson F, Cottier JP, Gissot V, El-Hage W, Camus V, Gohier B, Desmidt T; MEMENTO study group. Benzodiazepine use and neuroimaging markers of Alzheimer's disease in nondemented older individuals: an MRI and 18F Florbetapir PET study in the MEMENTO cohort. Neuropsychopharmacology. 2022 Apr;47(5):1114-1120. doi: 10.1038/s41386-021-01246-5. Epub 2021 Dec 10. PMID: 34893757; PMCID: PMC8938511.
Glasman P, Houot M, Migliaccio R, Bombois S, Gagliardi G, Cacciamani F, Habert MO, Dubois B, Epelbaum S; INSIGHT-PreAD study group. Subtle postoperative cognitive disorder in preclinical Alzheimer's disease. Exp Gerontol. 2022 May;161:111715. doi: 10.1016/j.exger.2022.111715. Epub 2022 Jan 29. PMID: 35104564.
Grasset L, Proust-Lima C, Mangin JF, Habert MO, Dubois B, Paquet C, Hanon O, Gabelle A, Ceccaldi M, Annweiler C, David R, Jonveaux T, Belin C, Julian A, Rouch-Leroyer I, Pariente J, Locatelli M, Chupin M, Chêne G, Dufouil C; Memento Cohort Study group. Explaining the association between social and lifestyle factors and cognitive functions: a pathway analysis in the Memento cohort. Alzheimers Res Ther. 2022 May 18;14(1):68. doi: 10.1186/s13195-022-01013-8. PMID: 35585559; PMCID: PMC9115948.
Mank A, van Maurik IS, Rijnhart JJM, Bakker ED, Bouteloup V, Le Scouarnec L, Teunissen CE, Barkhof F, Scheltens P, Berkhof J, van der Flier WM. Development of multivariable prediction models for institutionalization and mortality in the full spectrum of Alzheimer's disease. Alzheimers Res Ther. 2022 Aug 5;14(1):110. doi: 10.1186/s13195-022-01053-0. PMID: 35932034; PMCID: PMC9354423.
Mishra A, Duplaà C, Vojinovic D, Suzuki H, Sargurupremraj M, Zilhão NR, Li S, Bartz TM, Jian X, Zhao W, Hofer E, Wittfeld K, Harris SE, van der Auwera-Palitschka S, Luciano M, Bis JC, Adams HHH, Satizabal CL, Gottesman RF, Gampawar PG, Bülow R, Weiss S, Yu M, Bastin ME, Lopez OL, Vernooij MW, Beiser AS, Völker U, Kacprowski T, Soumare A, Smith JA, Knopman DS, Morris Z, Zhu Y, Rotter JI, Dufouil C, Valdés Hernández M, Muñoz Maniega S, Lathrop M, Boerwinkle E, Schmidt R, Ihara M, Mazoyer B, Yang Q, Joutel A, Tournier-Lasserve E, Launer LJ, Deary IJ, Mosley TH, Amouyel P, DeCarli CS, Psaty BM, Tzourio C, Kardia SLR, Grabe HJ, Teumer A, van Duijn CM, Schmidt H, Wardlaw JM, Ikram MA, Fornage M, Gudnason V, Seshadri S, Matthews PM, Longstreth WT, Couffinhal T, Debette S. Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate. Brain. 2022 Jun 30;145(6):1992-2007. doi: 10.1093/brain/awab432. PMID: 35511193; PMCID: PMC9255380.
Régy M, Dugravot A, Sabia S, Fayosse A, Mangin JF, Chupin M, Fischer C, Bouteloup V, Dufouil C, Chêne G, Paquet C, Hanseeuw B, Singh-Manoux A, Dumurgier J; MEMENTO cohort Study Group. Association of APOE ε4 with cerebral gray matter volumes in non-demented older adults: The MEMENTO cohort study. Neuroimage. 2022 Apr 15;250:118966. doi: 10.1016/j.neuroimage.2022.118966. Epub 2022 Feb 2. PMID: 35122970.
Rouanet A, Avila-Rieger J, Dugravot A, Lespinasse J, Stuckwisch R, Merrick R, Anderson E, Long L, Helmer C, Jacqmin-Gadda H, Dufouil C, Judd S, Manly J, Sabia S, Gross A, Proust-Lima C. How Selection Over Time Contributes to the Inconsistency of the Association Between Sex/Gender and Cognitive Decline Across Cognitive Aging Cohorts. Am J Epidemiol. 2022 Feb 19;191(3):441-452. doi: 10.1093/aje/kwab227. PMID: 34521111; PMCID: PMC9214252.
Sakr FA, Grothe MJ, Cavedo E, Jelistratova I, Habert MO, Dyrba M, Gonzalez-Escamilla G, Bertin H, Locatelli M, Lehericy S, Teipel S, Dubois B, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Correction: Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: the INSIGHT-preAD study. Alzheimers Res Ther. 2022 Sep 14;14(1):131. doi: 10.1186/s13195-022-01025-4. Erratum for: Alzheimers Res Ther. 2019 Jan 31;11(1):15. PMID: 36104713; PMCID: PMC9472399.
Sarnowski C, Ghanbari M, Bis JC, Logue M, Fornage M, Mishra A, Ahmad S, Beiser AS, Boerwinkle E, Bouteloup V, Chouraki V, Cupples LA, Damotte V, DeCarli CS, DeStefano AL, Djoussé L, Fohner AE, Franz CE, Kautz TF, Lambert JC, Lyons MJ, Mosley TH, Mukamal KJ, Pase MP, Portilla Fernandez EC, Rissman RA, Satizabal CL, Vasan RS, Yaqub A, Debette S, Dufouil C, Launer LJ, Kremen WS, Longstreth WT, Ikram MA, Seshadri S. Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels. Commun Biol. 2022 Apr 8;5(1):336. doi: 10.1038/s42003-022-03287-y. PMID: 35396452; PMCID: PMC8993877.
Spinelli G, Bakardjian H, Schwartz D, Potier MC, Habert MO, Levy M, Dubois B, George N; INSIGHT-preAD Study Group. Theta Band-Power Shapes Amyloid-Driven Longitudinal EEG Changes in Elderly Subjective Memory Complainers At-Risk for Alzheimer's Disease. J Alzheimers Dis. 2022;90(1):69-84. doi: 10.3233/JAD-220204. PMID: 36057818; PMCID: PMC9661330.
2021
Chamberlain JD, Rouanet A, Dubois B, Pasquier F, Hanon O, Gabelle A, Ceccaldi M, Krolak-Salmon P, Béjot Y, Godefroy O, Wallon D, Gentric A, Chêne G, Dufouil C; Memento Study group. Investigating the association between cancer and the risk of dementia: Results from the Memento cohort. Alzheimers Dement. 2021Sep;17(9):1415-1421. doi: 10.1002/alz.12308 . Epub 2021 Mar 3. PMID: 33656287;
PMCID: PMC8518910.
Frison E, Proust-Lima C, Mangin JF, Habert MO, Bombois S, Ousset PJ, Pasquier F, Hanon O, Paquet C, Gabelle A, Ceccaldi M, Annweiler C, Krolak-Salmon P, Béjot Y, Belin C, Wallon D, Sauvee M, Beaufils E, Bourdel-Marchasson I, Jalenques I, Chupin M, Chêne G, Dufouil C; MEMENTO Cohort Study Group. Diabetes Mellitus and Cognition: Pathway Analysis in the MEMENTO Cohort. Neurology. 2021 Aug
24;97(8):e836-e848. doi: 10.1212/WNL.0000000000012440. Epub 2021 Jul 1. PMID: 34210821; PMCID: PMC8397583.
Gaubert S, Houot M, Raimondo F, Ansart M, Corsi MC, Naccache L, Sitt JD, Habert MO, Dubois B, De Vico Fallani F, Durrleman S, Epelbaum S; INSIGHT-preAD study group. A machine learning approach to screen for preclinical Alzheimer's disease. Neurobiol Aging. 2021 Sep;105:205-216. doi: 10.1016/j.neurobiolaging.2021.04.024 . Epub 2021 May 4.PMID: 34102381
Henry V, Moszer I, Dameron O, Vila Xicota L, Dubois B, Potier MC, Hofmann-Apitius M, Colliot O; INSIGHT-preAD Study Group. Converting disease maps into heavyweight ontologies: general methodology and application to Alzheimer's disease. Database (Oxford). 2021 Feb 16;2021:baab004. doi: 10.1093/database/baab004. PMID: 33590873; PMCID: PMC7937031.
Kühnel L, Bouteloup V, Lespinasse J, Chêne G, Dufouil C, Molinuevo JL, Raket LL; MEMENTO study group and the Alzheimer's Disease Neuroimaging Initiative. Personalized prediction of progression in pre-dementia patients based on individual biomarker profile: A development and validation study. Alzheimers Dement. 2021 Dec;17(12):1938-1949. doi: 10.1002/alz.12363 . Epub 2021 Sep 28. PMID: 34581496.
Lemercier P, Vergallo A, Lista S, Zetterberg H, Blennow K, Potier MC, Habert MO, Lejeune FX, Dubois B, Teipel S, Hampel H; INSIGHT-preAD study group and the Alzheimer Precision Medicine Initiative (APMI). Association of plasma Aβ40/Aβ42 ratio and brain Aβ accumulation: testing a whole-brain PLS-VIP approach in individuals at risk of Alzheimer's disease. Neurobiol Aging. 2021 Nov;107:57-69. doi: 10.1016/j.neurobiolaging.2021.07.005. Epub 2021 Jul 14. PMID: 34388400.
Miao R, Chen HY, Robert P, Smith EE, Ismail Z; MEMENTO Study Group. White matter hyperintensities and mild behavioral impairment: Findings from the MEMENTO cohort study. Cereb Circ Cogn Behav. 2021 Sep 14;2:100028. doi: 10.1016/j.cccb.2021.100028. PMID: 36324720; PMCID: PMC9616384.
Penner G, Lecocq S, Chopin A, Vedoya X, Lista S, Vergallo A, Cavedo E, Lejeune FX, Dubois B, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Aptamarker prediction of brain amyloid-β status in cognitively normal individuals at risk for Alzheimer's disease. PLoS One. 2021 Jan 4;16(1):e0243902. doi: 10.1371/journal.pone.0243902. eCollection 2021.PMID: 33395442
Planche V, Bouteloup V, Mangin JF, Dubois B, Delrieu J, Pasquier F, Blanc F, Paquet C, Hanon O, Gabelle A, Ceccaldi M, Annweiler C, Krolak-Salmon P, Habert MO, Fischer C, Chupin M, Béjot Y, Godefroy O, Wallon D, Sauvée M, Bourdel-Marchasson I, Jalenques I, Tison F, Chêne G, Dufouil C; the MEMENTO Study group. Clinical relevance of brain atrophy subtypes categorization in memory clinics. Alzheimers Dement. 2021 Apr;17(4):641-652. doi: 10.1002/alz.12231. Epub 2020 Dec 15. PMID: 33325121.
Teipel SJ, Dyrba M, Vergallo A, Lista S, Habert MO, Potier MC, Lamari F, Dubois B, Hampel H, Grothe MJ. Partial Volume Correction Increases the Sensitivity of 18F-Florbetapir-Positron Emission Tomography for the Detection of Early Stage Amyloidosis. Front Aging Neurosci. 2021 Dec 22;13:748198. doi: 10.3389/fnagi.2021.748198 . eCollection 2021.PMID: 35002673
Vergallo A, Lemercier P, Cavedo E, Lista S, Vanmechelen E, De Vos A, Zetterberg H, Blennow K, Habert MO, Potier MC, Dubois B, Teipel S, Hampel H; INSIGHT-preAD study group, and the Alzheimer Precision Medicine Initiative (APMI). Plasma β-secretase1 concentrations correlate with basal forebrain atrophy and neurodegeneration in cognitively healthy individuals at risk for AD. Alzheimers Dement. 2021 Apr;17(4):629-640. doi: 10.1002/alz.12228. Epub 2021 Feb 1. PMID: 33527718.
Vergallo A, Lista S, Zhao Y, Lemercier P, Teipel SJ, Potier MC, Habert MO, Dubois B, Lukiw WJ, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). MiRNA-15b and miRNA-125b are associated with regional Aβ-PET and FDG-PET uptake in cognitively normal individuals with subjective memory complaints. Transl Psychiatry. 2021 Jan 27;11(1):78. doi: 10.1038/s41398-020-01184-8. PMID: 33504764; PMCID: PMC7840941.
2020
Babiloni C, Lopez S, Del Percio C, Noce G, Pascarelli MT, Lizio R, Teipel SJ, González-Escamilla G, Bakardjian H, George N, Cavedo E, Lista S, Chiesa PA, Vergallo A, Lemercier P, Spinelli G, Grothe MJ, Potier MC, Stocchi F, Ferri R, Habert MO, Fraga FJ, Dubois B, Hampel H; INSIGHT-preAD Study Group. Resting-state posterior alpha rhythms are abnormal in subjective memory complaint seniors with preclinical Alzheimer's neuropathology and high education level: the INSIGHT-preAD study. Neurobiol Aging. 2020 Jun;90:43-59. doi: 10.1016/j.neurobiolaging.2020.01.012 . Epub 2020 Feb 1. PMID: 32111391
Baldacci F, Lista S, Manca ML, Chiesa PA, Cavedo E, Lemercier P, Zetterberg H, Blennow K, Habert MO, Potier MC, Dubois B, Vergallo A, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Age and sex impact plasma NFL and t-Tau trajectories in individuals with subjective memory complaints: a 3-year follow-up study. Alzheimers Res Ther. 2020 Nov 12;12(1):147. doi: 10.1186/s13195-020-00704-4 .PMID: 33183357
Bauermeister S, Orton C, Thompson S, Barker RA, Bauermeister JR, Ben-Shlomo Y, Brayne C, Burn D, Campbell A, Calvin C, Chandran S, Chaturvedi N, Chêne G, Chessell IP, Corbett A, Davis DHJ, Denis M, Dufouil C, Elliott P, Fox N, Hill D, Hofer SM, Hu MT, Jindra C, Kee F, Kim CH, Kim C, Kivimaki M, Koychev I, Lawson RA, Linden GJ, Lyons RA, Mackay C, Matthews PM, McGuiness B, Middleton L, Moody C, Moore K, Na DL, O'Brien JT, Ourselin S, Paranjothy S, Park KS, Porteous DJ, Richards M, Ritchie CW, Rohrer JD, Rossor MN, Rowe JB, Scahill R, Schnier C, Schott JM, Seo SW, South M, Steptoe M, Tabrizi SJ, Tales A, Tillin T, Timpson NJ, Toga AW, Visser PJ, Wade-Martins R, Wilkinson T, Williams J, Wong A, Gallacher JEJ. The Dementias Platform UK (DPUK) Data Portal. Eur J Epidemiol. 2020 Jun;35(6):601-611. doi: 10.1007/s10654-020-00633-4. Epub 2020 Apr 23. PMID: 32328990; PMCID: PMC7320955.
Cacciamani F, Sambati L, Houot M, Habert MO, Dubois B, Epelbaum S; INSIGHT-PreAD study group. Awareness of cognitive decline trajectories in asymptomatic individuals at risk for AD. Alzheimers Res Ther. 2020 Oct 14;12(1):129. doi: 10.1186/s13195-020-00700-8 . PMID: 33054821; PMCID: PMC7557018.
Cavedo E, Lista S, Houot M, Vergallo A, Grothe MJ, Teipel S, Zetterberg H, Blennow K, Habert MO, Potier MC, Dubois B, Hampel H; INSIGHT-preAD Study Group, Alzheimer Precision Medicine Initiative. Plasma tau correlates with basal forebrain atrophy rates in people at risk for Alzheimer disease. Neurology. 2020 Jan 7;94(1):e30-e41. doi: 10.1212/WNL.0000000000008696 . Epub 2019 Dec 4. PMID: 31801830.
Chiesa PA, Houot M, Vergallo A, Cavedo E, Lista S, Potier MC, Zetterberg H, Blennow K, Vanmechelen E, De Vos A, Dubois B, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Association of brain network dynamics with plasma biomarkers in subjective memory complainers. Neurobiol Aging. 2020 Apr;88:83-90. doi: 10.1016/j.neurobiolaging.2019.12.017 . Epub 2019 Dec 23. PMID: 32087948.
Dauphinot V, Bouteloup V, Mangin JF, Vellas B, Pasquier F, Blanc F, Hanon O, Gabelle A, Annweiler C, David R, Planche V, Godefroy O, Rivasseau-Jonveaux T, Chupin M, Fischer C, Chêne G, Dufouil C, Krolak-Salmon P. Subjective cognitive and non-cognitive complaints and brain MRI biomarkers in the MEMENTO cohort. Alzheimers Dement (Amst). 2020 Jul 5;12(1):e12051. doi: 10.1002/dad2.12051 .PMID: 32647745; PMCID: PMC7335902.
Delabar JM, Ortner M, Simon S, Wijkhuisen A, Feraudet-Tarisse C, Pegon J, Vidal E, Hirschberg Y, Dubois B, Potier MC. Altered age-linked regulation of plasma DYRK1A in elderly cognitive complainers (INSIGHT-preAD study) with high brain amyloid load. Alzheimers Dement (N Y). 2020 Jul 2;6(1):e12046. doi: 10.1002/trc2.12046 . PMID: 32642550; PMCID: PMC7331462.
Gagliardi G, Houot M, Cacciamani F, Habert MO, Dubois B, Epelbaum S; for ADNI; for the INSIGHT-preAD study group. The meta-memory ratio: a new cohort-independent way to measure cognitive awareness in asymptomatic individuals at risk for Alzheimer's disease. Alzheimers Res Ther. 2020 May 14;12(1):57. doi: 10.1186/s13195-020-00626-1. PMID: 32408882; PMCID: PMC7222501.
Janssen O, Vos SJB, García-Negredo G, Tochel C, Gustavsson A, Smith M, Ly A, Nelson M, Baldwin H, Sudlow C, Bexelius C, Jindra C, Vaci N, Bauermeister S, Gallacher J, Ponjoan A, Dufouil C, Garre Olmo J, Pedersen L, Skoog I, Hottgenroth A, Visser PJ, van der Lei J, Diaz C. Real-world evidence in Alzheimer's disease: The ROADMAP Data Cube. Alzheimers Dement. 2020 Mar;16(3):461-471. doi: 10.1016/j.jalz.2019.09.087 . Epub 2020 Jan 6. PMID: 32157788.
Teipel SJ, Dyrba M, Chiesa PA, Sakr F, Jelistratova I, Lista S, Vergallo A, Lemercier P, Cavedo E, Habert MO, Dubois B, Hampel H, Grothe MJ; INSIGHT-preAD study group and for the Alzheimerś Disease Neuroimaging Initiative. In vivo staging of regional amyloid deposition predicts functional conversion in the preclinical and prodromal phases of Alzheimer's disease. Neurobiol Aging. 2020 Sep;93:98-108. doi: 10.1016/j.neurobiolaging.2020.03.011 . Epub 2020 Mar 17. PMID: 32291113.
Vergallo A, Lista S, Lemercier P, Chiesa PA, Zetterberg H, Blennow K, Potier MC, Habert MO, Baldacci F, Cavedo E, Caraci F, Dubois B, Hampel H; INSIGHT-preAD study group and the Alzheimer Precision Medicine Initiative (APMI); INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Association of plasma YKL-40 with brain amyloid-β levels, memory performance, and sex in subjective memory complainers. Neurobiol Aging. 2020 Dec;96:22-32. doi: 10.1016/j.neurobiolaging.2020.07.009 . Epub 2020 Aug 17. PMID: 32920471.
Vonk JMJ, Bouteloup V, Mangin JF, Dubois B, Blanc F, Gabelle A, Ceccaldi M, Annweiler C, Krolak-Salmon P, Belin C, Rivasseau-Jonveaux T, Julian A, Sellal F, Magnin E, Chupin M, Habert MO, Chêne G, Dufouil C; MEMENTO cohort Study Group. Semantic loss marks early Alzheimer's disease-related neurodegeneration in older adults without dementia. Alzheimers Dement (Amst). 2020 Aug 5;12(1):e12066. doi: 10.1002/dad2.12066 . PMID: 32775598; PMCID: PMC7403823.
2019
Chiesa PA, Cavedo E, Vergallo A, Lista S, Potier MC, Habert MO, Dubois B, Thiebaut de Schotten M, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease. Alzheimers Dement. 2019 Jul;15(7):940-950. doi: 10.1016/j.jalz.2019.03.006. Epub 2019 May 18. PMID: 31113760.
Chiesa PA, Cavedo E, Grothe MJ, Houot M, Teipel SJ, Potier MC, Habert MO, Lista S, Dubois B, Hampel H; INSIGHT-preAD Study Group and the Alzheimer Precision Medicine Initiative (APMI). Relationship between Basal Forebrain Resting-State Functional Connectivity and Brain Amyloid-β Deposition in Cognitively Intact Older Adults with Subjective Memory Complaints. Radiology. 2019 Jan;290(1):167-176. doi: 10.1148/radiol.2018180268 . Epub 2018 Oct 23. PMID: 30351255.
Ettore E, Bakardjian H, Solé M, Levy Nogueira M, Habert MO, Gabelle A, Dubois B, Robert P, David R. Relationships between objectives sleep parameters and brain amyloid load in subjects at risk for Alzheimer's disease: the INSIGHT-preAD Study. Sleep. 2019 Sep 6;42(9):zsz137. doi: 10.1093/sleep/zsz137. PMID: 31267124.
Gaubert S, Raimondo F, Houot M, Corsi MC, Naccache L, Diego Sitt J, Hermann B, Oudiette D, Gagliardi G, Habert MO, Dubois B, De Vico Fallani F, Bakardjian H, Epelbaum S; Alzheimer’s Disease Neuroimaging Initiative. EEG evidence of compensatory mechanisms in preclinical Alzheimer's disease. Brain. 2019 Jul 1;142(7):2096-2112. doi: 10.1093/brain/awz150. PMID: 31211359.
Gagliardi G, Epelbaum S, Houot M, Bakardjian H, Boukadida L, Revillon M, Dubois B, Dalla Barba G, La Corte V; INSIGHT-preAD study group. Which Episodic Memory Performance is Associated with Alzheimer's Disease Biomarkers in Elderly Cognitive Complainers? Evidence from a Longitudinal Observational Study with Four Episodic Memory Tests (Insight-PreAD). J Alzheimers Dis. 2019;70(3):811-824. doi: 10.3233/JAD-180966 .PMID: 31282413
Pase MP, Beiser AS, Himali JJ, Satizabal CL, Aparicio HJ, DeCarli C, Chêne G, Dufouil C, Seshadri S. Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes. JAMA Neurol. 2019 May 1;76(5):598-606. doi: 10.1001/jamaneurol.2018.4666 . PMID: 30830207; PMCID: PMC6515589.
Sakr FA, Grothe MJ, Cavedo E, Jelistratova I, Habert MO, Dyrba M, Gonzalez-Escamilla G, Bertin H, Locatelli M, Lehericy S, Teipel S, Dubois B, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: the INSIGHT-preAD study. Alzheimers Res Ther. 2019 Jan 31;11(1):15. doi: 10.1186/s13195-019-0466-3 . PMID: 30704537; PMCID: PMC6357385
Slot RER, Sikkes SAM, Berkhof J, Brodaty H, Buckley R, Cavedo E, Dardiotis E, Guillo-Benarous F, Hampel H, Kochan NA, Lista S, Luck T, Maruff P, Molinuevo JL, Kornhuber J, Reisberg B, Riedel-Heller SG, Risacher SL, Roehr S, Sachdev PS, Scarmeas N, Scheltens P, Shulman MB, Saykin AJ, Verfaillie SCJ, Visser PJ, Vos SJB, Wagner M, Wolfsgruber S, Jessen F; Alzheimer's Disease Neuroimaging Initiative; DESCRIPA working group; INSIGHT-preAD study group; SCD-I working group; van der Flier WM. Subjective cognitive decline and rates of incident Alzheimer's disease and non-Alzheimer's disease dementia. Alzheimers Dement. 2019 Mar;15(3):465-476. doi: 10.1016/j.jalz.2018.10.003. Epub 2018 Dec 13. PMID: 30555032; PMCID: PMC6465066.
Taillard J, Sagaspe P, Berthomier C, Brandewinder M, Amieva H, Dartigues JF, Rainfray M, Harston S, Micoulaud-Franchi JA, Philip P. Non-REM Sleep Characteristics Predict Early Cognitive Impairment in an Aging Population. Front Neurol. 2019 Mar 13;10:197. doi: 10.3389/fneur.2019.00197 . PMID: 30918496; PMCID: PMC6424890.
Toschi N, Lista S, Baldacci F, Cavedo E, Zetterberg H, Blennow K, Kilimann I, Teipel SJ, Melo Dos Santos A, Epelbaum S, Lamari F, Genthon R, Habert MO, Dubois B, Floris R, Garaci F, Vergallo A, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Biomarker-guided clustering of Alzheimer's disease clinical syndromes. Neurobiol Aging. 2019 Nov;83:42-53. doi: 10.1016/j.neurobiolaging.2019.08.032. Epub 2019 Sep 10. PMID: 31585366.
Vergallo A, Houot M, Cavedo E, Lemercier P, Vanmechelen E, De Vos A, Habert MO, Potier MC, Dubois B, Lista S, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD. Alzheimers Dement. 2019 Oct;15(10):1274-1285. doi: 10.1016/j.jalz.2019.07.001. PMID: 31627825.
Vergallo A, Mégret L, Lista S, Cavedo E, Zetterberg H, Blennow K, Vanmechelen E, De Vos A, Habert MO, Potier MC, Dubois B, Neri C, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Plasma amyloid β 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease. Alzheimers Dement. 2019 Jun;15(6):764-775. doi: 10.1016/j.jalz.2019.03.009 . Epub 2019 May 18. PMID: 31113759.
Villeneuve SC, Houot M, Cacciamani F, Verrijp M, Dubois B, Sikkes S, Epelbaum S; MEMENTO study group and the INSIGHT-preAD study group. Latent class analysis identifies functional decline with Amsterdam IADL in preclinical Alzheimer's disease. Alzheimers Dement (N Y). 2019 Oct 8;5:553-562. doi: 10.1016/j.trci.2019.08.009 . PMID: 31650012; PMCID: PMC6804616.
Xicota L, Ichou F, Lejeune FX, Colsch B, Tenenhaus A, Leroy I, Fontaine G, Lhomme M, Bertin H, Habert MO, Epelbaum S, Dubois B, Mochel F, Potier MC; INSIGHT study group. Multi-omics signature of brain amyloid deposition in asymptomatic individuals at-risk for Alzheimer's disease: The INSIGHT-preAD study. EBioMedicine. 2019 Sep;47:518-528. doi: 10.1016/j.ebiom.2019.08.051 . Epub 2019 Sep 3. PMID: 31492558; PMCID: PMC6796577.
2018
Cavedo E, Chiesa PA, Houot M, Ferretti MT, Grothe MJ, Teipel SJ, Lista S, Habert MO, Potier MC, Dubois B, Hampel H; INSIGHT-preAD Study Group; Alzheimer Precision Medicine Initiative (APMI). Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in cognitively normal older adults with subjective memory complaints. Alzheimers Dement. 2018 Sep;14(9):1204-1215. doi: 10.1016/j.jalz.2018.05.014 . Epub 2018 Jul 7. PMID: 30201102.
Dubois B, Epelbaum S, Nyasse F, Bakardjian H, Gagliardi G, Uspenskaya O, Houot M, Lista S, Cacciamani F, Potier MC, Bertrand A, Lamari F, Benali H, Mangin JF, Colliot O, Genthon R, Habert MO, Hampel H; INSIGHT-preAD study group. Cognitive and neuroimaging features and brain β-amyloidosis in individuals at risk of Alzheimer's disease (INSIGHT-preAD): a longitudinal observational study. Lancet Neurol. 2018 Apr;17(4):335-346. doi: 10.1016/S1474-4422(18)30029-2 . Epub 2018 Feb 27. Erratum in: Lancet Neurol. 2018 Apr 25;: PMID: 29500152.
Epelbaum S, Bouteloup V, Mangin JF, La Corte V, Migliaccio R, Bertin H, Habert MO, Fischer C, Azouani C, Fillon L, Chupin M, Vellas B, Pasquier F, Dartigues JF, Blanc F, Gabelle A, Ceccaldi M, Krolak-Salmon P, Hugon J, Hanon O, Rouaud O, David R, Chêne G, Dubois B, Dufouil C. Neural correlates of episodic memory in the Memento cohort. Alzheimers Dement (N Y). 2018 May 22;4:224-233. doi: 10.1016/j.trci.2018.03.010 . PMID: 29955665; PMCID: PMC6021546.
Habert MO, Bertin H, Labit M, Diallo M, Marie S, Martineau K, Kas A, Causse-Lemercier V, Bakardjian H, Epelbaum S, Chételat G, Houot M, Hampel H, Dubois B, Mangin JF; INSIGHT-AD study group. Evaluation of amyloid status in a cohort of elderly individuals with memory complaints: validation of the method of quantification and determination of positivity thresholds. Ann Nucl Med. 2018 Feb;32(2):75-86. doi: 10.1007/s12149-017-1221-0 . Epub 2017 Dec 7. PMID: 29218458.
Mendes A, Tezenas du Montcel S, Levy M, Bertrand A, Habert MO, Bertin H, Dubois B, Epelbaum S; INSIGHT-PreAD study group. Multimorbidity Is Associated with Preclinical Alzheimer's Disease Neuroimaging Biomarkers. Dement Geriatr Cogn Disord. 2018;45(5-6):272-281. doi: 10.1159/000489007 . Epub 2018 Jun 28. PMID: 29953971.
Teipel SJ, Cavedo E, Lista S, Habert MO, Potier MC, Grothe MJ, Epelbaum S, Sambati L, Gagliardi G, Toschi N, Greicius MD, Dubois B, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Effect of Alzheimer's disease risk and protective factors on cognitive trajectories in subjective memory complainers: An INSIGHT-preAD study. Alzheimers Dement. 2018 Sep;14(9):1126-1136. doi: 10.1016/j.jalz.2018.04.004 . Epub 2018 May 21. PMID: 29792873.
Vergallo A, Bun RS, Toschi N, Baldacci F, Zetterberg H, Blennow K, Cavedo E, Lamari F, Habert MO, Dubois B, Floris R, Garaci F, Lista S, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Association of cerebrospinal fluid α-synuclein with total and phospho- tau(181) protein concentrations and brain amyloid load in cognitively normal subjective memory complainers stratified by Alzheimer's disease biomarkers. Alzheimers Dement. 2018 Dec;14(12):1623- 1631. doi: 10.1016/j.jalz.2018.06.3053 . Epub 2018 Jul 26. PMID: 30055132.
2017
Cacciamani F, Tandetnik C, Gagliardi G, Bertin H, Habert MO, Hampel H, Boukadida L, Révillon M, Epelbaum S, Dubois B; INSIGHT-PreAD study group. Low Cognitive Awareness, but Not Complaint, is a Good Marker of Preclinical Alzheimer's Disease. J Alzheimers Dis. 2017;59(2):753-762. doi: 10.3233/JAD-170399 . PMID: 28671134.
Dufouil C, Dubois B, Vellas B, Pasquier F, Blanc F, Hugon J, Hanon O, Dartigues JF, Harston S, Gabelle A, Ceccaldi M, Beauchet O, Krolak-Salmon P, David R, Rouaud O, Godefroy O, Belin C, Rouch I, Auguste N, Wallon D, Benetos A, Pariente J, Paccalin M, Moreaud O, Hommet C, Sellal F, Boutoleau-Bretonniére C, Jalenques I, Gentric A, Vandel P, Azouani C, Fillon L, Fischer C, Savarieau H, Operto G, Bertin H, Chupin M, Bouteloup V, Habert MO, Mangin JF, Chêne G; MEMENTO cohort Study Group. Cognitive and imaging markers in non-demented subjects attending a memory clinic: study design and baseline findings of the MEMENTO cohort. Alzheimers Res Ther. 2017 Aug 29;9(1):67. doi: 10.1186/s13195-017-0288-0 . PMID: 28851447; PMCID: PMC5576287.
Kaaouana T, Bertrand A, Ouamer F, Law-Ye B, Pyatigorskaya N, Bouyahia A, Thiery N, Dufouil C, Delmaire C, Dormont D, de Rochefort L, Chupin M. Improved cerebral microbleeds detection using their magnetic signature on T2*-phase-contrast: A comparison study in a clinical setting. Neuroimage Clin. 2016 Aug 9;15:274-283. doi: 10.1016/j.nicl.2016.08.005 . PMID: 28560152; PMCID: PMC5435598.
Teipel S, Bakardjian H, Gonzalez-Escamilla G, Cavedo E, Weschke S, Dyrba M, Grothe MJ, Potier MC, Habert MO, Dubois B, Hampel H; INSIGHT-preAD study group. No association of cortical amyloid load and EEG connectivity in older people with subjective memory complaints. Neuroimage Clin. 2017 Oct 29;17:435-443. doi: 10.1016/j.nicl.2017.10.031 . PMID: 29159056; PMCID: PMC5684495.
Teipel SJ, Cavedo E, Weschke S, Grothe MJ, Rojkova K, Fontaine G, Dauphinot L, Gonzalez-Escamilla G, Potier MC, Bertin H, Habert MO, Dubois B, Hampel H; INSIGHT-preAD study group. Cortical amyloid accumulation is associated with alterations of structural integrity in older people with subjective memory complaints. Neurobiol Aging. 2017 Sep;57:143-152. doi: 10.1016/j.neurobiolaging.2017.05.016 . Epub 2017 May 31. PMID: 28646687.
2016
Habert MO, Marie S, Bertin H, Reynal M, Martini JB, Diallo M, Kas A; CATI Nuclear Medicine network; Trébossen R. Optimization of brain PET imaging for a multicentre trial: the French CATI experience. EJNMMI Phys. 2016 Dec;3(1):6. doi: 10.1186/s40658-016-0141-8. Epub 2016 Apr 5. PMID: 27044410; PMCID: PMC4820434.